Institutional Animal Care and Use Committee
The University
of Illinois at Urbana-Champaign
Institutional Animal Care and Use Committee |
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The University
of Illinois at Urbana-Champaign
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Example of a search for available alternatives in polyclonal antibody production:
Database Searched:
BIOSIS Previews (1980 - 3/98)
Date of Search:
6/16/98
Search Strategy:
"Vitro" = 280,177 records
"Alternative" = 54,561 records
"Pain" and "Stress" and "Distress" and "Welfare" and "Discomfort" = 134,438 records
"Rabbit" and "Lagomorph" = 89,973 records
"Antibod*" = 267,349 records
The combination of all of the above
searches = 23 records
Results:
Of the 23 titles retrieved, 1 appeared
relevant to the topic of alternatives to animal and specific adjuvant use in
polyclonal antibody production (based on title and abstract).
Titles Found (bold indicates relevancy):
1. Organization of non-muscle myosin during early murine embryonic differentiation.
2. A soluble form of Fc-gamma-RIII is present in human serum and other body fluids and is elevated at sites of inflammation.
3. Enhancement of heme oxygenase-1 synthesis by glutathione depletion in Chinese hamster ovary cells.
4. Corneal keratocytes: In situ and in vitro organization of cytoskeletal contractile proteins.
5. Induction of glucose regulated proteins during growth of a murine tumor.
6. An immunological assessment of group-housed rabbits.
7. Nerve growth factor antibody stimulates reactivation of ocular herpes simplex virus type 1 in latently infected rabbits.
8. Oxidation-specific epitopes in human coronary atherosclerosis are not limited to oxidized low-density lipoprotein.
9. The Specific NH-2-terminal Sequence Ac-EEED of alpha-Smooth Muscle Actin Plays a Role in Polymerization In Vitro and In Vivo.
10. Diversity of neuronal phenotypes expressed in monolayer cultures from immature rabbit retina.
11. Histochemical localization of heme oxygenase-2 protein and mRNA expression in rat brain.
12. Effect of alterations of blood cholesterol levels on macrophages in the myocardium of New Zealand White rabbits.
13. Quantitation of Nitrotyrosine Levels in Lung Sections of Patients and Animals with Acute lung Injury.
14. Factor XIII is not involved in human platelet-collagen interaction.
15. Functional analysis and quantification of the complement C3 derived anaphylatoxin C3a with a monoclonal antibody.
16. Effects of anti-C5a antibodies on the adult respiratory distress syndrome in septic primates.
17. Microvascular pericytes contain muscle and nonmuscle actins.
18. Casbene synthetase: Regulation of phytoalexin biosynthesis in Ricinus communis seedlings: Purification of casbene synthetase and regulation of its biosynthesis during elicitation.
19. Microtubule-associated proteins: A monoclonal antibody to MAP 1 decorates microtubules in vitro but strains stress fibers and not microtubules in vivo.
20. A sensitive direct enzyme immunoassay for cortisol in plasma and saliva.
21. Highly purified pp60-src induces the actin transformation in microinjected cells and phosphorylates selected cytoskeletal proteins in vitro.
22. Evidence for the transsynaptic activation of tyrosine hydroxylase in rabbit portal vein mediated through a cyclic AMP-independent mechanism.
23. Fodrin: Axonally transported
polypeptides associated with the internal periphery of many cells.
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